EMTRICITABINE (FTC)

Patent Holder: Gilead Sciences

Date: July 2011

In July 2011, the Medicines Patent Pool (MPP) signed a licence agreement with Gilead Sciences for several antiretrovirals. It included a covenant not to sue on products containing emtricitabine (FTC). FTC is recommended by the World Health Organization (WHO) as a component of first and second-line treatment regimens for adults and children.

In September 2017, the two parties amended the agreement to allow for an extension of the Territory for FTC to Belarus, Malaysia, Ukraine and Philippines. Together, the extended territory is home to 90.5% of people living with HIV in low- and middle-income countries.

In September 2019, the agreement with Gilead Sciences mentioned above was amended to allow for the inclusion of Azerbaijan to the territory of now 117 countries.

— Licence Agreement

— AMENDMENT TO LICENCE AGREEMENT - SEPTEMBER 2017

— Sublicence Agreement - Form for existing licensees in India

— AMENDMENT TO SUBLICENCE AGREEMENT - FORM FOR EXISTING LICENSEES IN INDIA

— Sublicence Agreement - Form for new licensees in India

— AMENDMENT TO SUBLICENCE AGREEMENT - FORM FOR NEW LICENSEES IN INDIA

— Sublicence Agreement - Form for new licensees in China

— AMENDMENT TO SUBLICENCE AGREEMENT - FORM FOR NEW LICENSEES IN CHINA

— Sublicence Agreement - Form for new licensees in South Africa

— AMENDMENT TO SUBLICENCE AGREEMENT - FORM FOR NEW LICENSEES IN SOUTH AFRICA

Key Features

*Eligibility:*	All entities based in China, India and South Africa that have signed the licence with Gilead and MPP on TDF, TAF, COBI and EVG, regardless of whether they have terminated TDF or not.
*Geographical scope for sale:*	The geographical scope is 112 countries, representing 90.5% of people living with HIV in low- and middle-income countries, equivalent to the territory included in the TDF and TAF licences.
*Sales outside the licensed territory:*	The covenant not to sue only applies to the 112 countries included. Sales outside the licensed territory may be possible if not infringing on any granted patents.
*Royalties:*	No royalties on the covenant not to sue (but there may be royalties on other components of any specific combination)
*Combinations:*	The covenant not to sue covers combinations that include FTC, such as TDF/FTC, TAF/FTC and TDF/FTC/EFV
*Patent disclosure:*	The covenant not to sue discloses the list of all pending and granted patents in the 112 licensed countries at the time of signing the licence
*Termination (or unbundling)*	Licensees that have terminated TDF continue to benefit from the covenant not to sue on TDF/FTC, TAF/FTC and TDF/FTC/EFV.

See related licence

Announcement

Board resolution

Advisory Group Report

Country List

Afghanistan, Angola, Anguilla, Antigua and Barbuda, Armenia, Aruba, Azerbaijan, Bahamas, Bangladesh, Barbados, Belarus, Belize, Benin, Bhutan, Bolivia (Plurinational State of), Botswana, Virgin Islands (British), Burkina Faso, Burundi, Cambodia, Cameroon, Cabo Verde, Central African Republic, Chad, Comoros, Côte d'Ivoire, Cuba, Congo, democratic Republic of the, Djibouti, Dominica, Dominican Republic, Ecuador, El Salvador, Equatorial Guinea, Eritrea, Eswatini, Ethiopia, Fiji, Gabon, Gambia (the), Georgia, Ghana, Grenada, Guatemala, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, India, Indonesia, Jamaica, Kazakhstan, Kenya, Kiribati, Kyrgyzstan, Lao People's Democratic Republic (the), Lesotho, Liberia, Madagascar, Malawi, Malaysia, Maldives, Mali, Mauritius, Mauritania, Moldova, Republic of, Mongolia, Montserrat, Mozambique, Myanmar, Namibia, Nauru, Nepal, Nicaragua, Niger, Nigeria, Pakistan, Palau, Papua New Guinea, Congo, Rwanda, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Samoa, Sao Tome and Principe, Senegal, Seychelles, Sierra Leone, Solomon Islands, Somalia, South Africa, South Sudan, Sri Lanka, Sudan, Suriname, Syrian Arab Republic, Tajikistan, Tanzania, United Republic of, Thailand, Timor-Leste, Togo, Tonga, Trinidad and Tobago, Turkmenistan, Turks and Caicos Islands, Tuvalu, Uganda, Ukraine, Uzbekistan, Vanuatu, Viet Nam, Yemen, Zambia, Zimbabwe