The Medicines Patent Pool publishes framework for prioritising target medicines for in-licensing under its newly expanded mandate
The MPP published in May a prioritisation framework that outlines a precise methodology for assessing candidate medicines that could play a major role in the MPP’s expanded mandate into new disease therapies beyond HIV, hepatitis C and tuberculosis.
The Medicines Patent Pool (MPP) is a United Nations-backed public health organisation working to increase access to, and facilitate the development of, life-saving medicines for low- and middle-income countries.
The MPP’s patents and licences database, MedsPaL, is a resource that provides information on the intellectual property status of selected HIV, hepatitis C, tuberculosis and other patented essential medicines in low- and middle-income countries.
Geneva, 1 December 2019 — On World AIDS Day, the Medicines Patent Pool (MPP) announces a sublicence agreement with Indian manufacturing partner Cipla for the development, manufacture and supply of HIV treatment lopinavir (LPV) and ritonavir (RTV or r) individually or in combination, for paediatric use.
LPV boosted with RTV (LPV/r) is recommended by the World Health Organization (WHO) as a component of first- and second-line HIV treatment regimens for neonates and children.
“According to UNAIDS, only half of the 1.7 million children living with HIV receives antiretroviral therapy, largely because of the dearth of appropriate formulations adapted for children of different ages and weight bands,” says Charles Gore, Executive Director of MPP. “Cipla’s engagement with MPP is a very positive sign for all the children living with HIV in developing countries who will soon be able to access this key HIV treatment.”
The licence agreement signed by MPP with patent holder Abbvie in November 2014 permits generic...
Geneva, 27 November 2019 – The Government of South Africa announces today the roll-out of HIV medicine dolutegravir (DTG). The World Health Organization recommends DTG-based treatment as the preferred first- and second-line regimen for people living with HIV.
The Medicines Patent Pool (MPP), through public health-oriented licensing agreements with ViiV Healthcare signed in 2014, has facilitated accelerated access to quality-assured, affordable versions of DTG and its combinations, including TLD, the fixed dose combination of tenofovir disoproxil fumarate, lamivudine and DTG.
South Africa, benefiting from these access agreements, is the country with the highest number of people living with HIV, with 7.7 million people affected by the disease, and with the largest HIV treatment programme in the world with 4.8 million people already on antiretroviral treatment, largely through the public health sector.
“The Government of South Africa has been a leader in the HIV response and a valued partner of MPP for...
Geneva, 28 October 2019 — The Medicines Patent Pool (MPP) today announced a licence agreement with Pfizer to facilitate the clinical development of sutezolid, an investigational medicine for the treatment of tuberculosis (TB). The drug candidate, if further developed in combination with other drugs, could be used to more effectively treat patients diagnosed with TB, particularly multidrug-resistant TB (MDR-TB).
“TB, especially MDR-TB, has become a health security threat and finding new treatments for patients is now an urgent global public health priority. We must accelerate progress if we aim to put an end to the epidemic by 2030,” said Charles Gore, Executive Director of the Medicines Patent Pool. “The licence agreement we just signed with Pfizer is key for any organisation willing to further develop sutezolid and make it available for people who need it the most, especially in low- and middle-income countries.”
Pfizer is granting MPP a non-exclusive, worldwide and royalty-free licence allowing potent...
“We support the engagement of all relevant organizations, such as WHO, UNAIDS, Gavi, the Global Fund, and Unitaid and initiatives, including the recent expansion of the Medicines Patent Pool, in their work to improve access for all to safe, effective, quali...”
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