Ensuring Global Pandemic Preparedness

MPP contributed to the fourth Implementation Report of the 100 Days Mission that has just been released by the International Pandemic Preparedness Secretariat. The Report is a critical initiative aimed at ensuring global access to diagnostics, therapeutics, and vaccines (DTVs) within 100 days of a Public Health Emergency of International Concern (PHEIC). This report, unveiled at an event co-hosted with the South African Department of Health and the South African Medical Research Council (SAMRC) in Cape Town on 31 January 2025, highlights the progress and challenges in achieving a 100-day response to future pandemics.

Key Highlights:

  • Global Preparedness: Despite national bright spots, the world remains unprepared for another global pandemic, five years after the COVID-19 PHEIC declaration.
  • 100 Days Mission Scorecard 2.0: The latest scorecard reveals limited progress in newly approved diagnostics, therapeutics, and vaccines, with critical gaps remaining in the development and deployment of these essential tools.
  • Evolving Threats: The report underscores the urgency of building a robust and equitable R&D ecosystem as the world continues to grapple with evolving threats like the resurgence of Mpox, Marburg, and Ebola, and the spread of H5N1 with the first human fatalities recorded.

What’s Inside the Report:

  • Progress in 2024: An overview of the progress made towards the 100 Days Mission in 2024.
  • Challenges and Opportunities: An analysis of the challenges, risks, and opportunities on the horizon for medical countermeasure development.
  • Priority Actions for 2025: Key priority action areas for the upcoming year.
  • 100 Days Mission Scorecard 2.0: An assessment of readiness, funding, and R&D pipelines for the expanded WHO priority pathogens with high pandemic potential.
  • Mpox Case Study: An in-depth analysis of the ongoing Mpox response through a 100 Days Mission lens.
  • Rwanda’s Success: A highlight of Rwanda’s successful response to the 2024 Marburg outbreak, demonstrating the principles of the 100 Days Mission in action.

Access the Report